![]() Meftahi GH, Jangravi Z, Sahraei H, Bahari Z.A Novel Coronavirus from Patients with Pneumonia in China, 2019. ![]() Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W.Human Coronaviruses: A Review of Virus-Host Interactions. Keywords: acute respiratory distress syndrome (ARDS), COVID-19, cytokine storm, oxidative stress We also described how aging can inflame the vicious circle. In this review, we discussed molecular mechanisms of a fatal vicious circle between oxidative stress and cytokine storm during COVID-19 infection. Cytokine storm and oxidative stress are the main players of ARDS development during respiratory virus infections. Acute respiratory distress syndrome (ARDS) is considered as a defining cause of the death cases. Since then, it has propagated rapidly and turned into a major global crisis due to the high virus spreading. In early December 2019, the pandemic of coronavirus disease 2019 (COVID-19) began in Wuhan City, Hubei Province, China. *e-mail: 31 August 2020 Accepted: 17 December 2020 Iman 3,5ġNeuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran ĢDepartment of Physiology and Medical Physics, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran ģNanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran ĤDepartment of Biochemistry, Faculty of Medicine, Baqiyatallah University of Medical Sciences, Tehran, Iran ĥDepartment of Pharmaceutics, Faculty of Pharmacy, Baqiyatallah University of Medical Sciences, Tehran, Iran ![]()
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